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Nathaniel, a young Berkeley biologist, met a beautiful yeast who promised opportunity and adventure, but once they got together, Nathaniel was clumsy, the yeast not what he'd hoped, and their romance? Well, it didn't work out. It's now a song. Sung by Nathaniel. The yeast, lacking vocal chords, is silent.

Ann Powers picks her favorite chart-topping, radio-dominating songs of 2012.

What do singer Gotye, Chinese artist Liu Bolin and early 20th century painter Abbott Handerson Thayer have in common? (Here's a hint: Look very, very closely.)

As summer fades, we bid an official farewell to the year's biggest pop hit, Gotye's unlikely smash, "Somebody That I Used To Know."

Known for the infectious "Somebody That I Used To Know" Gotye will be opening a North American tour right here in Colorado at Red Rocks. The show is…